Pfizer and UCB form new drug-discovery company with support of UK Technology Strategy Board

October 2008

Pfizer Ltd (NYSE:PFE) (LSE:PFZ) and Brussels-based UCB are to form a new company, called Cyclofluidic, a breakthrough technology company established with the aim of significantly accelerating the drug discovery process by allowing researchers to test a greater range of potential new medicines in a shorter time. The UK Government’s Technology Strategy Board has helped facilitate this innovative arrangement between Pfizer and UCB and will continue to support Cyclofluidic by co-funding its R&D.

The aim of Cyclofluidic is to develop technologies that automate and integrate processes known as flow chemistry and flow biology to help pharmaceutical companies shorten timelines within the drug development process.

Explaining the background to the Technology Strategy Board’s support, its Chief Executive, Iain Gray, said: “Our role is to stimulate the development and deployment of technologies which, as well as benefiting society, also provide global business opportunities for the UK. Cyclofluidic is an excellent example of the private and public sectors working together to develop world-leading technologies which have the potential to bring enormous benefit to patients in the UK and around the world. We are delighted to offer our support and investment."

“Cyclofluidic’s entry into the rapidly evolving microfluidic technology area has the potential to radically transform the medicinal chemistry and biology interface.” Says Dr Neil Weir, Senior Vice President Research at UCB. “It’s an exciting opportunity for UCB and Pfizer to collaborate and offers real potential for improved productivity, underlining our commitment to innovation for patients.”

Dr Annette Doherty, Vice President and Research Head at Pfizer’s European R&D Headquarters said “We are extremely pleased to collaborate with UCB and the Technology Strategy Board to help improve efficiency in the drug development process. We are excited by the potential of this new partnership to help us identify the most effective medicines for later stages of development and — ultimately — create new and improved therapies for patients.”

Peter Luke, Senior Director, Worldwide Business Development at Pfizer said, “This is a great example of how public-private partnerships can provide innovative technologies to speed medicines to market. We are impressed by the way the Technology Strategy Board has initiated a novel and creative deal structure.”

Cyclofluidic will be jointly owned by Pfizer and UCB, with each company having both a seat and scientific observer rights on the board.

Currently, it takes between 12-15 years and a cost of up to £500 million to develop a new medicine. One of the most time-intensive and skilful parts of pharmaceutical research is the screening of potential medicines against therapeutic targets.

Cyclofluidic will develop a microfluidic closed loop lead optimisation platform which will enable researchers to access state of the art expertise in flow chemistry, flow screening and microfluidic engineering. This will be addressed through extensive collaboration with key academics and component manufacturers

Cyclofluidic will also provide training for both flow chemistry and biology scientists at its facility, to be located in the South of England.

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